The effects of host diversity on vector-borne disease: the conditions under which diversity will amplify or dilute the disease risk.

Multihost vector-borne infectious diseases form a significant fraction of the global infectious disease burden.In this study we explore the relationship between host diversity, vector behavior, and disease risk.To this end, we have developed a new dynamic model which includes two distinct host species and one vector species with variable preference

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Dynamic thresholding and tissue dissociation optimization for CITE-seq identifies differential surface protein abundance in metastatic melanoma

Abstract Multi-omics profiling ORG PITTED PRUNE by CITE-seq bridges the RNA-protein gap in single-cell analysis but has been largely applied to liquid biopsies.Applying CITE-seq to clinically relevant solid biopsies to characterize healthy tissue and the tumor microenvironment is an essential next step in single-cell translational studies.In this s

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